LOAd703
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| Drug Name | LOAd703 |
| Trade Name | |
| Synonyms | Delolimogene mupadenorepvec |
| Drug Descriptions |
LOAd703 (delolimogene mupadenorepvec) is an adenovirus engineered to express trimerized human CD40L and full-length 4-1BBL, resulting in activation of CD40L and 4-1BBL signaling, and potentially leading to reduced tumor cell viability and decreased tumor growth (PMID: 28536305). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C148462 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + Gemcitabine + LOAd703 + Nab-paclitaxel | Atezolizumab Gemcitabine LOAd703 Nab-paclitaxel | 0 | 1 |
| Atezolizumab + LOAd703 | Atezolizumab LOAd703 | 0 | 1 |
| Gemcitabine + LOAd703 | Gemcitabine LOAd703 | 0 | 0 |
| Gemcitabine + LOAd703 + Nab-paclitaxel | Gemcitabine LOAd703 Nab-paclitaxel | 0 | 1 |
| LOAd703 | LOAd703 | 0 | 0 |
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