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Drug Name | LOAd703 |
Trade Name | |
Synonyms | Delolimogene mupadenorepvec |
Drug Descriptions |
LOAd703 (delolimogene mupadenorepvec) is an adenovirus engineered to express trimerized human CD40L and full-length 4-1BBL, resulting in activation of CD40L and 4-1BBL signaling, and potentially leading to reduced tumor cell viability and decreased tumor growth (PMID: 28536305). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C148462 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Gemcitabine + LOAd703 + Nab-paclitaxel | Atezolizumab Gemcitabine LOAd703 Nab-paclitaxel | 0 | 1 |
Atezolizumab + LOAd703 | Atezolizumab LOAd703 | 0 | 1 |
Gemcitabine + LOAd703 | Gemcitabine LOAd703 | 0 | 0 |
Gemcitabine + LOAd703 + Nab-paclitaxel | Gemcitabine LOAd703 Nab-paclitaxel | 0 | 1 |
LOAd703 | LOAd703 | 0 | 0 |