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Drug Name | CX-2029 |
Trade Name | |
Synonyms | PDC-targeting CD71 CX-2029|CX 2029 |
Drug Descriptions |
CX-2029 is a probody-drug conjugate that consists of CD71-targeted monoclonal antibody linked to a antigen-binding site masking peptide that is conjugated to the anti-microtubule agent monomethyl auristatin E (MMAE), which potentially induces cell cycle arrest and apoptosis of CD71-expressing tumor cells (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C153287 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CX-2029 | CX-2029 | 0 | 1 |