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| Drug Name | Y27632 |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
Y27632 is an inhibitor of Rho-associated protein kinase (ROCK1), which may block cellular adhesion, and lead to inhibition of colony formation and enhancement of cell detachment when combined with chemotherapeutic agents (PMID: 31160603, PMID: 23392171). |
| DrugClasses | |
| CAS Registry Number | 146986-50-7 |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Paclitaxel + Y27632 | Paclitaxel Y27632 | 0 | 0 |
| Y27632 | Y27632 | 0 | 0 |