Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | LY3499446 |
Trade Name | |
Synonyms | LY-3499446|LY 3499446 |
Drug Descriptions |
LY3499446 is an oral inhibitor of KRAS G12C that prevents constitutive downstream signaling to inhibit tumor cell proliferation and growth (PMID: 32014824). |
DrugClasses | KRAS G12C inhibitor 34 |
CAS Registry Number | NA |
NCIT ID | C166410 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abemaciclib + LY3499446 | Abemaciclib LY3499446 | 0 | 1 |
Cetuximab + LY3499446 | Cetuximab LY3499446 | 0 | 1 |
Erlotinib + LY3499446 | Erlotinib LY3499446 | 0 | 1 |
LSN3321213 + LY3499446 | LSN3321213 LY3499446 | 0 | 0 |
LY3499446 | LY3499446 | 0 | 1 |