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Drug Name | TR1801-ADC |
Trade Name | |
Synonyms | MT8633|MT 8633|TR 1801|anti-c-Met ADC TR1801|TR1801 |
Drug Descriptions |
TR1801-ADC is an antibody-drug conjugate comprising a Met monoclonal antibody linked to a pyrrolobenzodiazepine dimer (PBD)-toxin, which delivers the toxin to Met-expressing tumor cells, potentially resulting in inhibition of DNA replication and decreased cell proliferation (PMID: 31736230). |
DrugClasses | MET Antibody 31 |
CAS Registry Number | NA |
NCIT ID | C158513 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Gemcitabine + TR1801-ADC | Gemcitabine TR1801-ADC | 0 | 0 |
TR1801-ADC | TR1801-ADC | 0 | 1 |