TR1801-ADC
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| Drug Name | TR1801-ADC |
| Trade Name | |
| Synonyms | MT8633|MT 8633|TR 1801|anti-c-Met ADC TR1801|TR1801 |
| Drug Descriptions |
TR1801-ADC is an antibody-drug conjugate comprising a Met monoclonal antibody linked to a pyrrolobenzodiazepine dimer (PBD)-toxin, which delivers the toxin to Met-expressing tumor cells, potentially resulting in inhibition of DNA replication and decreased cell proliferation (PMID: 31736230). |
| DrugClasses | MET Antibody 37 |
| CAS Registry Number | NA |
| NCIT ID | C158513 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Gemcitabine + TR1801-ADC | Gemcitabine TR1801-ADC | 0 | 0 |
| TR1801-ADC | TR1801-ADC | 0 | 1 |
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