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Drug Name | MAK683 |
Trade Name | |
Synonyms | MAK 683|EED PPI inhibitor MAK683 |
Drug Descriptions |
MAK683 blocks the interaction between EED and EZH2, potentially resulting in a loss of PRC2 activity, reduced H3K27 trimethylation, and decreased proliferation of tumor cells (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 3083, PMID: 36858198). |
DrugClasses | |
CAS Registry Number | 1951408-58-4 |
NCIT ID | C133819 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
MAK683 | MAK683 | 0 | 1 |