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Drug Name Fluzoparib
Trade Name
Synonyms HS10160|SHR-3162|SHR3162|Fuzuloparib
Drug Descriptions

Fluzoparib (SHR3162) is a PARP inhibitor, which potentially induces DNA damage, cell cycle arrest and apoptosis, and inhibits cell proliferation and tumor growth (PMID: 30663191, PMID: 32694901).

DrugClasses PARP Inhibitor (Pan) 31
CAS Registry Number 1358715-18-0
NCIT ID C126274

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Fluzoparib + Prednisone Abiraterone Fluzoparib Prednisone 0 1
Fluzoparib Fluzoparib 0 0
Fluzoparib + HS10241 Fluzoparib HS10241 0 0
Fluzoparib + SHR-1316 Fluzoparib SHR-1316 0 0
Fluzoparib + Temozolomide Fluzoparib Temozolomide 0 0


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