Fluzoparib
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| Drug Name | Fluzoparib |
| Trade Name | |
| Synonyms | HS10160|SHR-3162|SHR3162|Fuzuloparib |
| Drug Descriptions |
Fluzoparib (SHR3162) is a PARP inhibitor, which potentially induces DNA damage, cell cycle arrest and apoptosis, and inhibits cell proliferation and tumor growth (PMID: 30663191, PMID: 32694901). |
| DrugClasses | PARP Inhibitor (Pan) 29 |
| CAS Registry Number | 1358715-18-0 |
| NCIT ID | C126274 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abiraterone + Fluzoparib + Prednisone | Abiraterone Fluzoparib Prednisone | 0 | 1 |
| Fluzoparib | Fluzoparib | 0 | 0 |
| Fluzoparib + HS10241 | Fluzoparib HS10241 | 0 | 0 |
| Fluzoparib + SHR-1316 | Fluzoparib SHR-1316 | 0 | 0 |
| Fluzoparib + Temozolomide | Fluzoparib Temozolomide | 0 | 0 |
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