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Drug Name | SAR441000 |
Trade Name | |
Synonyms | SAR 441000|SAR-441000|BNT 131|BNT131|BNT-131 |
Drug Descriptions |
SAR441000 is a mixture of mRNA encoding IL-12sc, IL-15sushi, IFNa and GM-CSF that may be taken up by cells, translated, and released into the tumor microenvironment, potentially resulting in increased antitumor immune response (NCI Drug Dictionary; Cancer Res (2023) 83 (8_Supplement): LB198). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C166375 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cemiplimab + SAR441000 | Cemiplimab SAR441000 | 0 | 1 |
SAR441000 | SAR441000 | 0 | 1 |