Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | SAR441000 |
| Trade Name | |
| Synonyms | SAR 441000|SAR-441000|BNT 131|BNT131|BNT-131 |
| Drug Descriptions |
SAR441000 is a mixture of mRNA encoding IL-12sc, IL-15sushi, IFNa and GM-CSF that may be taken up by cells, translated, and released into the tumor microenvironment, potentially resulting in increased antitumor immune response (NCI Drug Dictionary; Cancer Res (2023) 83 (8_Supplement): LB198). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C166375 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Cemiplimab + SAR441000 | Cemiplimab SAR441000 | 0 | 1 |
| SAR441000 | SAR441000 | 0 | 1 |