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Drug Name | IPH5301 |
Trade Name | |
Synonyms | IPH-5301|IPH 5301|IPH53|IPH 53 |
Drug Descriptions |
IPH5301 is a monoclonal antibody that binds to and inhibits soluble and membrane-bound CD73, thereby blocking synthesis of adenosine from AMP, which potentially leads to activation of T-lymphocytes and antitumor immune response (PMID: 31116985). |
DrugClasses | CD73 Antibody 12 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
IPH5301 | IPH5301 | 0 | 1 |
IPH5301 + Paclitaxel + Trastuzumab | IPH5301 Paclitaxel Trastuzumab | 0 | 1 |