Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | GTB-3550 TriKE |
Trade Name | |
Synonyms | CD16/IL-15/CD33 TriKE|161533 TriKE|GTB3550 |
Drug Descriptions |
GTB-3550 TriKE is a tri-specific killer engager molecule that binds to CD16 and CD33 and contains an IL-15 crosslinker, which potentially enhances proliferation of NK-cells, induces cytotoxicity against CD33-expressing tumor cells, and reduces tumor burden (PMID: 26847056). |
DrugClasses | CD33 Antibody 13 |
CAS Registry Number | NA |
NCIT ID | C151948 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
GTB-3550 TriKE | GTB-3550 TriKE | 0 | 1 |