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Drug Name | CD19-CD34 CAR transduced T-cells |
Trade Name | |
Synonyms | CD19-CD34t Metabolically Programmed CAR T-cells |
Drug Descriptions |
CD19-CD34 CAR transduced T-cells are metabolically enhanced T lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19 and selected for CD34 expression, which potentially induce toxicity in CD19-expressing tumor cells (NCI Drug Dictionary). |
DrugClasses | CD19 Immune Cell Therapy 64 |
CAS Registry Number | NA |
NCIT ID | C202931 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CD19-CD34 CAR transduced T-cells | CD19-CD34 CAR transduced T-cells | 0 | 1 |
CD19-CD34 CAR transduced T-cells + Cyclophosphamide + Fludarabine | CD19-CD34 CAR transduced T-cells Cyclophosphamide Fludarabine | 0 | 1 |