Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | PRT543 |
Trade Name | |
Synonyms | PRT-543|PRT 543 |
Drug Descriptions |
PRT543 is an inhibitor of PRMT5, which inhibits PRMT5 methyltransferase activity, leading to decreased histone H2A, H3, and H4 arginine mono and di-methylation and altered expression of genes involved in cellular processes, thereby potentially resulting in decreased tumor cell growth (NCI Drug Dictionary). |
DrugClasses | PRMT5 Inhibitor 17 |
CAS Registry Number | NA |
NCIT ID | C162454 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
PRT543 | PRT543 | 0 | 1 |