JNJ-64619178
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| Drug Name | JNJ-64619178 |
| Trade Name | |
| Synonyms | JNJ64619178|JNJ 64619178 |
| Drug Descriptions |
JNJ-64619178 is a PRMT5 inhibitor that binds to and inhibits the S-adenosylmethionine (SAM) and substrate-binding regions of the PRMT5/MEP50 complex, potentially reducing dimethylation of target proteins such as SMD1/3 and resulting in tumor growth inhibition (Cancer Res 2018;78(13 Suppl):Abstract nr 4859, PMID: 31312965). |
| DrugClasses | PRMT5 Inhibitor 21 |
| CAS Registry Number | 2086772-26-9 |
| NCIT ID | C163980 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| JNJ-64619178 | JNJ-64619178 | 0 | 1 |
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