CE7R CAR-T cells
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| Drug Name | CE7R CAR-T cells |
| Trade Name | |
| Synonyms | CD171 CAR+ T Cells|CD171-specific CAR-CD28 zeta-4-1-BB-EGFRt-expressing T cells |
| Drug Descriptions |
CE7R CAR-T cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD171 and containing CD28, CD3zeta, and TNFRSF9 (4-1BB) signaling domains and truncated EGFR, which potentially induces cytotoxicity in CD171-expressing tumors (PMID: 27390347). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C119746 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CE7R CAR-T cells | CE7R CAR-T cells | 0 | 1 |
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