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Drug Name | BAY2287411 |
Trade Name | |
Synonyms | BAY-2287411|BAY 2287411|Th 227 Anetumab |
Drug Descriptions |
BAY2287411 is a radioimmunoconjugate consisting of the radionuclide thorium-227 linked to the mesothelin (MSLN) targeting antibody BAY 86-1903 (anetumab), which induces DNA damage and cell cycle arrest, potentially resulting in increased apoptosis, reduced cell viability, and inhibition of tumor growth (PMID: 31064781). |
DrugClasses | MSLN Antibody 12 |
CAS Registry Number | NA |
NCIT ID | C155977 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
BAY2287411 | BAY2287411 | 0 | 1 |