Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | GS-1423 |
| Trade Name | |
| Synonyms | AGEN1423|AGEN 1423|AGEN-1423|GS1423|GS 1423|Dalutrafusp alfa |
| Drug Descriptions |
GS-1423 is an aglycosylated bispecific antibody that targets CD73 and TGFbeta, potentially resulting in antitumor activity (PMID: 36746510). |
| DrugClasses | CD73 Antibody 14 TGFB (Pan) Antibody 5 |
| CAS Registry Number | NA |
| NCIT ID | C167206 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Balstilimab + Botensilimab + GS-1423 | Balstilimab Botensilimab GS-1423 | 0 | 1 |
| Balstilimab + Gemcitabine + GS-1423 + Nab-paclitaxel | Balstilimab GS-1423 Gemcitabine Nab-paclitaxel | 0 | 1 |
| Balstilimab + GS-1423 | Balstilimab GS-1423 | 0 | 1 |
| Fluorouracil + GS-1423 + Leucovorin + Oxaliplatin | Fluorouracil GS-1423 Leucovorin Oxaliplatin | 0 | 1 |
| GS-1423 | GS-1423 | 0 | 1 |