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Drug Name | GS-1423 |
Trade Name | |
Synonyms | AGEN1423|AGEN 1423|AGEN-1423|GS1423|GS 1423|Dalutrafusp alfa |
Drug Descriptions |
GS-1423 is an aglycosylated bispecific antibody that targets CD73 and TGFbeta, potentially resulting in antitumor activity (PMID: 36746510). |
DrugClasses | CD73 Antibody 12 TGFB (Pan) Antibody 5 |
CAS Registry Number | NA |
NCIT ID | C167206 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Balstilimab + Botensilimab + GS-1423 | Balstilimab Botensilimab GS-1423 | 0 | 1 |
Balstilimab + Gemcitabine + GS-1423 + Nab-paclitaxel | Balstilimab GS-1423 Gemcitabine Nab-paclitaxel | 0 | 1 |
Balstilimab + GS-1423 | Balstilimab GS-1423 | 0 | 1 |
Fluorouracil + GS-1423 + Leucovorin + Oxaliplatin | Fluorouracil GS-1423 Leucovorin Oxaliplatin | 0 | 1 |
GS-1423 | GS-1423 | 0 | 1 |