CTX110
Drug Detail
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| Drug Name | CTX110 |
| Trade Name | |
| Synonyms | CTX-110|CTX 110|anti-CD19 CAR CRISPR-edited CTX110 |
| Drug Descriptions |
CTX110 consists of a preparation of allogeneic T-lymphocytes engineered with CRISPR/Cas9 to express a chimeric antigen receptor (CAR) targeting CD19 and to simultaneously remove the endogenous T cell receptor, which potentially reduces GVHD and induces killing of tumor cells overexpressing CD19 (NCI Drug Dictionary). |
| DrugClasses | CD19 Immune Cell Therapy 72 |
| CAS Registry Number | NA |
| NCIT ID | C165492 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CTX110 | CTX110 | 0 | 1 |
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