iC9.GD2.CAR.IL-15 T-cells
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| Drug Name | iC9.GD2.CAR.IL-15 T-cells |
| Trade Name | |
| Synonyms | |
| Drug Descriptions |
iC9.GD2.CAR.IL-15 T-cells comprise T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets the disialoganglioside GD2 linked to CD28 and CD3zeta domains, as well as IL-15, and inducible caspase-9, which potentially induces cytotoxicity against tumor cells expressing GD2 and inhibits tumor growth (PMID: 30617136). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C158732 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| iC9.GD2.CAR.IL-15 T-cells | iC9.GD2.CAR.IL-15 T-cells | 0 | 2 |
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