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| Drug Name | TP-1454 |
| Trade Name | |
| Synonyms | TP1454|TP 1454 |
| Drug Descriptions |
TP-1454 is a pyruvate kinase M2 (PKM2) activator, which may inhibit tumor cell viability and tumor growth, and enhance anti-tumor immune response in combination with other agents (Mol Cancer Ther December 1 2019 (18) (12 Supplement) B080). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C175380 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Ipilimumab + Nivolumab + TP-1454 | Ipilimumab Nivolumab TP-1454 | 0 | 1 |
| TP-1454 | TP-1454 | 0 | 1 |
| TP-1454 + unspecified CTLA4 antibody | TP-1454 unspecified CTLA4 antibody | 0 | 0 |
| TP-1454 + unspecified CTLA4 antibody + unspecified PD-1 antibody | TP-1454 unspecified CTLA4 antibody unspecified PD-1 antibody | 0 | 0 |
| TP-1454 + unspecified PD-1 antibody | TP-1454 unspecified PD-1 antibody | 0 | 0 |