BRIP1 P727L
Gene Variant Detail

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Gene BRIP1
Variant P727L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions BRIP1 P727L does not lie within any known functional domains of the Brip1 protein (UniProt.org). P727L has not been characterized in the scientific literature and therefore, its effect on Brip1 protein function is unknown (PubMed, Feb 2026).
Associated Drug Resistance
Category Variants Paths

BRIP1 mutant BRIP1 P727L

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Transcript NM_032043.3
gDNA chr17:g.61744509G>A
cDNA c.2180C>T
Protein p.P727L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047436899.1 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
NM_032043.3 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
NM_032043 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_011525335.3 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_047436891.1 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_011525335.4 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_047436896.1 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_047436900.1 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_047436901.1 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_047436892.1 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
NM_032043.2 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_011525335 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38
XM_047436897.1 chr17:g.61744509G>A c.2180C>T p.P727L RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References