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| Gene | ABL1 |
| Variant | F401V |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | ABL1 F401V lies within the protein kinase domain of the Abl1 protein (UniProt.org). F401V has been identified in the scientific literature (PMID: 39440695), but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Jan 2026). |
| Associated Drug Resistance | |
| Category Variants Paths |
ABL1 mutant ABL1 F401V |
| Transcript | NM_005157.6 |
| gDNA | chr9:g.130874983T>G |
| cDNA | c.1201T>G |
| Protein | p.F401V |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_007313.3 | chr9:g.130874926T>G | c.1201T>G | p.F401V | RefSeq | GRCh38/hg38 |
| NM_005157.6 | chr9:g.130874983T>G | c.1201T>G | p.F401V | RefSeq | GRCh38/hg38 |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|