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| Gene | BRIP1 |
| Variant | F934V |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | BRIP1 F934V lies within the BRCA1-interacting region of the Brip1 protein (UniProt.org). F934V has not been characterized in the scientific literature and therefore, its effect on Brip1 protein function is unknown (PubMed, Feb 2026). |
| Associated Drug Resistance | |
| Category Variants Paths |
BRIP1 mutant BRIP1 F934V |
| Transcript | NM_032043.3 |
| gDNA | chr17:g.61685941A>C |
| cDNA | c.2800T>G |
| Protein | p.F934V |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| XM_011525335.3 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| NM_032043 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| NM_032043.3 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| XM_011525335 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| XM_011525335.4 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| XM_047436891.1 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| NM_032043.2 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| XM_047436892.1 | chr17:g.61685941A>C | c.2800T>G | p.F934V | RefSeq | GRCh38/hg38 |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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