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Gene | SMARCA4 |
Variant | A406T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | SMARCA4 A406T does not lie within any known functional domains of the Smarca4 protein (UniProt.org). A406T has been identified in sequencing studies (PMID: 22810696, PMID: 29316426), but has not been biochemically characterized and therefore, its effect on Smarca4 protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
SMARCA4 mutant SMARCA4 A406T |
Transcript | NM_003072.5 |
gDNA | chr19:g.10989414G>A |
cDNA | c.1216G>A |
Protein | p.A406T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_047439243.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128845 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128848 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128844.3 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_003072 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001374457.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_047439246.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451663.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451660.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027165 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451661.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128847.4 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001387283.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128849 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027161 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_011528198.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451663.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451658.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_047439251.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128848.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128844.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451659.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128845.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128846 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_006722845 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128848.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027168 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451666.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_003072.3 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451667.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_047439248.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128847 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451658.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451662.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_006722846.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_011528198.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_006722846.3 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451661.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451667.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027160 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128845.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128846.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_047439244.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001411150.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_047439249.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_047439250.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027164 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027167 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_011528198 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128847.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128849.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027162 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128849.3 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128844 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451665.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027166 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_017027163 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_006722846 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_006722845.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_001128846.2 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
NM_003072.5 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_024451664.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
XM_047439247.1 | chr19:g.10989414G>A | c.1216G>A | p.A406T | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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