Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene SMARCA4
Variant A406T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions SMARCA4 A406T does not lie within any known functional domains of the Smarca4 protein (UniProt.org). A406T has been identified in sequencing studies (PMID: 22810696, PMID: 29316426), but has not been biochemically characterized and therefore, its effect on Smarca4 protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

SMARCA4 mutant SMARCA4 A406T

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_003072.5
gDNA chr19:g.10989414G>A
cDNA c.1216G>A
Protein p.A406T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017027163 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451660.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128846 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439250.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451658.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128844 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027165 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128845 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128847.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_003072.5 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027168 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_006722846.3 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439243.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128848.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451667.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027161 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128846.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027160 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451658.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027162 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439247.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451666.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451661.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_006722846 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451663.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128845.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128849 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451667.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128846.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_003072.3 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439251.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128849.3 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_011528198.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128844.3 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451661.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439249.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128848 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128844.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001411150.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451659.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439244.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_011528198 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_006722846.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128847.4 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001387283.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027166 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451663.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451665.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128849.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027167 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128847 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128848.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439246.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_006722845 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001374457.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_001128845.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451664.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_006722845.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_024451662.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
NM_003072 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_011528198.2 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_017027164 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38
XM_047439248.1 chr19:g.10989414G>A c.1216G>A p.A406T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References