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Gene SMARCA4
Variant L180F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions SMARCA4 L180F lies within the QLQ domain of the Smarca4 protein (UniProt.org). L180F has not been characterized in the scientific literature and therefore, its effect on Smarca4 protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

SMARCA4 mutant SMARCA4 L180F

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Transcript NM_003072.5
gDNA chr19:g.10986371C>T
cDNA c.538C>T
Protein p.L180F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_003072 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128845.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128849 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128849.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027160 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451661.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451666.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128844.3 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128848.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_011528198.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439244.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128845 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451661.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439251.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128846.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027162 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027164 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_006722846 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027168 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001374457.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451658.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_003072.3 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128849.3 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128848.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451660.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439247.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451665.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451662.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128847 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439243.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451664.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451663.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451667.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027165 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_003072.5 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_006722846.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128847.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128846.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451659.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128847.4 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_006722845.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001411150.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128845.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027161 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001387283.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439246.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439248.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027166 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_006722846.3 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_011528198 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451658.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_011528198.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439249.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128848 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128844.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128846 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_047439250.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_006722845 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451663.2 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027167 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
NM_001128844 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_024451667.1 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38
XM_017027163 chr19:g.10986371C>T c.538C>T p.L180F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References