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Gene SMARCA4
Variant R370C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions SMARCA4 R370C does not lie within any known functional domains of the Smarca4 protein (UniProt.org). R370C has not been characterized in the scientific literature and therefore, its effect on Smarca4 protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

SMARCA4 mutant SMARCA4 R370C

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Transcript NM_003072.5
gDNA chr19:g.10987914C>T
cDNA c.1108C>T
Protein p.R370C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017027165 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001411150.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451666.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_003072.5 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_006722846.3 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_011528198.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027160 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128844.3 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451663.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439244.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439248.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_006722845.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128846.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128848.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128844 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128848.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027168 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128849 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027162 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451664.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451667.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_006722845 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451661.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027161 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128846 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_006722846 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451661.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451659.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027163 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451663.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451658.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439251.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027166 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_003072.3 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439250.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128847.4 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128844.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451667.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027167 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451660.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_011528198.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128845.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128848 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128847.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439243.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_003072 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451662.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451658.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128846.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_017027164 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001374457.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439246.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128849.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439249.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128845 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_011528198 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_006722846.2 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128845.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_047439247.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
XM_024451665.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128849.3 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001128847 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38
NM_001387283.1 chr19:g.10987914C>T c.1108C>T p.R370C RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References