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RET M918V - Gene Variant Detail

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Gene RET
Variant M918V
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions RET M918V lies within the protein kinase domain of the Ret protein (UniProt.org). M918V results in cell proliferation and foci formation to similar levels of wild-type Ret protein in culture (PMID: 21810974), and therefore, is predicted to have no effect on Ret protein function.
Associated Drug Resistance
Category Variants Paths

RET mutant RET M918X RET M918V

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Transcript NM_020975.6
gDNA chr10:g.43121967A>G
cDNA c.2752A>G
Protein p.M918V
Source Database RefSeq
Genome Build GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.