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Gene RET
Variant T338I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET T338I lies within the extracellular domain of the Ret protein (UniProt.org). T338I results in increased cell proliferation, but is not transforming in cell culture (PMID: 21810974), and therefore, its effect on Ret protein function is unknown.
Associated Drug Resistance
Category Variants Paths

RET mutant RET T338I

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Transcript NM_020975.6
gDNA chr10:g.43106521C>T
cDNA c.1013C>T
Protein p.T338I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406760.1 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_020975 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43111352C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_020630 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43111352C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43106521C>T c.1013C>T p.T338I RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries