AXL C117R
Gene Variant Detail

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Gene AXL
Variant C117R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions AXL C117R lies within Ig-like C2-type domain 1 of the Axl protein (UniProt.org). C117R has been identified in sequencing studies (PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Axl protein function is unknown (PubMed, Mar 2026).
Associated Drug Resistance
Category Variants Paths

AXL mutant AXL C117R

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Transcript NM_021913.5
gDNA chr19:g.41221186T>C
cDNA c.349T>C
Protein p.C117R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_021913.4 chr19:g.41221186T>C c.349T>C p.C117R RefSeq GRCh38/hg38
NM_001699.5 chr19:g.41221186T>C c.349T>C p.C117R RefSeq GRCh38/hg38
NM_001699.6 chr19:g.41221186T>C c.349T>C p.C117R RefSeq GRCh38/hg38
NM_021913.5 chr19:g.41221186T>C c.349T>C p.C117R RefSeq GRCh38/hg38
NM_021913 chr19:g.41221186T>C c.349T>C p.C117R RefSeq GRCh38/hg38
NM_001699 chr19:g.41221186T>C c.349T>C p.C117R RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References