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Gene RET
Variant F185L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET F185L lies within the Cadherin domain of the Ret protein (UniProt.org). F185L has not been characterized in the scientific literature and therefore, its effect on Ret protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET F185L

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Transcript NM_020975.6
gDNA chr10:g.43102557T>C
cDNA c.553T>C
Protein p.F185L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975.5 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_020630 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406781.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406785.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406771.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406773.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406769.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406782.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406780.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406763.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_020975 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406772.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406765.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406787.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38
NM_001406779.1 chr10:g.43102557T>C c.553T>C p.F185L RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References