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Gene | ALK |
Variant | K894T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ALK K894T lies within the extracellular domain of the Alk protein (UniProt.org). K894T has not been characterized in the scientific literature and therefore, its effect on Alk protein function is unknown (PubMed, Aug 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ALK mutant ALK K894T |
Transcript | NM_004304.5 |
gDNA | chr2:g.29229018T>G |
cDNA | c.2681A>C |
Protein | p.K894T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004304 | chr2:g.29229018T>G | c.2681A>C | p.K894T | RefSeq | GRCh38/hg38 |
NM_004304.5 | chr2:g.29229018T>G | c.2681A>C | p.K894T | RefSeq | GRCh38/hg38 |
NM_004304.4 | chr2:g.29229018T>G | c.2681A>C | p.K894T | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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