Starting April 21, you’ll be asked to log in or sign up for a free account after viewing 10 content pages each month.
Don’t worry—creating an account is quick and easy, and it comes with added benefits! Once logged in, you’ll not only continue accessing the content you already enjoy, but you’ll also unlock exclusive features like interactive donut plots for variant protein effects and variant impacts across the gene.
Stay tuned for these updates, and thank you for being part of our community!
Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | APC |
Variant | inact mut |
Impact List | unknown |
Protein Effect | loss of function |
Gene Variant Descriptions | APC inact mut indicates that this variant results in a loss of function of the Apc protein. However, the specific amino acid change has not been identified. |
Associated Drug Resistance | |
Category Variants Paths |
APC mutant APC inact mut |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
APC inact mut | loss of function | CTNNB1 Inhibitor Tankyrase Inhibitor |
APC inact mut PTEN inact mut |