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Gene | ALK |
Variant | amp |
Impact List | none |
Protein Effect | no effect |
Gene Variant Descriptions | ALK amplification indicates an increased number of copies of the ALK gene. However, the mechanism causing the increase is unspecified. |
Associated Drug Resistance | |
Category Variants Paths |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
ALK amp | no effect | |
ALK amp TP53 wild-type | ||
ALK rearrange ALK amp | ||
ALK F1174V ALK amp | ||
ALK F1174L ALK amp | ||
ALK amp ALK pos | ||
ALK F1174V ALK amp TP53 wild-type | ||
ALK F1174L ALK G1202R ALK D1203N ALK amp | ||
ALK del exon2 ALK del exon3 ALK amp | ||
ALK del exon2-3 ALK amp |