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| Gene | ALK |
| Variant | amp |
| Impact List | none |
| Protein Effect | no effect |
| Gene Variant Descriptions | ALK amplification indicates an increased number of copies of the ALK gene. However, the mechanism causing the increase is unspecified. |
| Associated Drug Resistance | |
| Category Variants Paths |
ALK amp |
| Molecular Profile | Protein Effect | Treatment Approaches |
|---|---|---|
| ALK amp | no effect | |
| ALK amp TP53 wild-type | ||
| ALK rearrange ALK amp | ||
| ALK F1174V ALK amp | ||
| ALK F1174L ALK amp | ||
| ALK amp ALK pos | ||
| ALK F1174V ALK amp TP53 wild-type | ||
| ALK F1174L ALK G1202R ALK D1203N ALK amp | ||
| ALK del exon2 ALK del exon3 ALK amp | ||
| ALK del exon2-3 ALK amp |