Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene | ALK |
| Variant | act mut |
| Impact List | unknown |
| Protein Effect | gain of function |
| Gene Variant Descriptions | ALK act mut indicates that this variant results in a gain of function in the Alk protein. However, the specific amino acid change has not been identified. |
| Associated Drug Resistance | |
| Category Variants Paths |
ALK mutant ALK act mut |
| Molecular Profile | Protein Effect | Treatment Approaches |
|---|---|---|
| ALK act mut | gain of function | ALK Inhibitor |
| ALK act mut TP53 wild-type |