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Gene | TSC1 |
Variant | del |
Impact List | deletion |
Protein Effect | loss of function |
Gene Variant Descriptions | TSC1 del indicates a deletion of the TSC1 gene. |
Associated Drug Resistance | |
Category Variants Paths |
TSC1 mutant TSC1 inact mut TSC1 del |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|---|---|---|---|---|---|
NCT06308419 | Phase I | Gemcitabine + Nab-rapamycin | A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions | Recruiting | USA | 0 |