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Gene MAP2K1
Variant D136Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MAP2K1 D136Y lies within the protein kinase domain of the Map2k1 protein (UniProt.org). D136Y has not been characterized in the scientific literature and therefore, its effect on Map2k1 protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

MAP2K1 mutant MAP2K1 D136Y

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Transcript NM_002755.4
gDNA chr15:g.66436860G>T
cDNA c.406G>T
Protein p.D136Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002755.3 chr15:g.66436860G>T c.406G>T p.D136Y RefSeq GRCh38/hg38
NM_002755.4 chr15:g.66436860G>T c.406G>T p.D136Y RefSeq GRCh38/hg38
XM_017022411.2 chr15:g.66436860G>T c.406G>T p.D136Y RefSeq GRCh38/hg38
XM_017022411.3 chr15:g.66436860G>T c.406G>T p.D136Y RefSeq GRCh38/hg38
XM_017022411 chr15:g.66436860G>T c.406G>T p.D136Y RefSeq GRCh38/hg38
NM_002755 chr15:g.66436860G>T c.406G>T p.D136Y RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References