ATRX T899M
Gene Variant Detail

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Gene ATRX
Variant T899M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATRX T899M does not lie within any known functional domains of the Atrx protein (UniProt.org). T899M has been identified in sequencing studies (PMID: 25550361), but has not been biochemically characterized and therefore, its effect on Atrx protein function is unknown (PubMed, Mar 2026).
Associated Drug Resistance
Category Variants Paths

ATRX mutant ATRX T899M

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Transcript NM_000489.6
gDNA chrX:g.77682560G>A
cDNA c.2696C>T
Protein p.T899M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000489 chrX:g.77682560G>A c.2696C>T p.T899M RefSeq GRCh38/hg38
XM_017029607 chrX:g.77682325_77682326delAGinsCA c.2696_2697delCTinsTG p.T899M RefSeq GRCh38/hg38
XM_006724668.3 chrX:g.77682560G>A c.2696C>T p.T899M RefSeq GRCh38/hg38
NM_000489.4 chrX:g.77682560G>A c.2696C>T p.T899M RefSeq GRCh38/hg38
XM_005262153.6 chrX:g.77682556_77682557delCCinsTG c.2696_2697delCCinsTG p.T899M RefSeq GRCh38/hg38
XM_005262153.5 chrX:g.77682556_77682557delCCinsTG c.2696_2697delCCinsTG p.T899M RefSeq GRCh38/hg38
XM_047442191.1 chrX:g.77682560G>A c.2696C>T p.T899M RefSeq GRCh38/hg38
XM_017029607.2 chrX:g.77682325_77682326delCTinsTG c.2696_2697delCTinsTG p.T899M RefSeq GRCh38/hg38
XM_006724668.4 chrX:g.77682560G>A c.2696C>T p.T899M RefSeq GRCh38/hg38
NM_000489.6 chrX:g.77682560G>A c.2696C>T p.T899M RefSeq GRCh38/hg38
XM_005262153 chrX:g.77682556_77682557delGGinsCA c.2696_2697delCCinsTG p.T899M RefSeq GRCh38/hg38
XM_006724668 chrX:g.77682560G>A c.2696C>T p.T899M RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References