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| Gene | PTEN |
| Variant | inact mut |
| Impact List | unknown |
| Protein Effect | loss of function |
| Gene Variant Descriptions | PTEN inact mut indicates that this variant results in a loss of function of the Pten protein. However, the specific amino acid change has not been identified. |
| Associated Drug Resistance | |
| Category Variants Paths |
PTEN mutant PTEN inact mut |
| Molecular Profile | Protein Effect | Treatment Approaches |
|---|---|---|
| PTEN inact mut | loss of function | Akt Inhibitor (Pan) Akt1 Inhibitor Akt2 Inhibitor PI3K Inhibitor (Pan) PIK3CB inhibitor |
| BRAF mut PTEN inact mut | ||
| PIK3CA wild-type PTEN inact mut | ||
| PIK3CA D1029Y PTEN inact mut | ||
| APC inact mut PTEN inact mut | ||
| HRAS G13R PTEN inact mut |