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Gene RET
Variant R912L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET R912L lies within the protein kinase domain of the Ret protein (UniProt.org). R912L has not been characterized and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET R912L

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Transcript NM_020975.6
gDNA chr10:g.43121950G>T
cDNA c.2735G>T
Protein p.R912L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020630 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_020975.6 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_020975 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43121950G>T c.2735G>T p.R912L RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Protein Effect Treatment Approaches
RET R912L unknown