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Gene | RET |
Variant | V915_K916insVHR |
Impact List | insertion |
Protein Effect | unknown |
Gene Variant Descriptions | RET V915_K916insVHR results in the insertion of three amino acids in the protein kinase domain of the Ret protein between amino acids 915 and 916 (UniProt.org). V915_K916insVHR has not been characterized in the scientific literature and therefore, its effect on Ret protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
RET mutant RET V915_K916insVHR |
Transcript | NM_020975.6 |
gDNA | chr10:g.43121960_43121961insGTACATAGG |
cDNA | c.2745_2746insGTACATAGG |
Protein | p.V915_K916insVHR |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_020630 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_020630.5 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_001406743.1 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_001406744.1 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_020975.5 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_001406759.1 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_001406760.1 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_020630.7 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_020975.6 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
NM_020975 | chr10:g.43121960_43121961insGTACATAGG | c.2745_2746insGTACATAGG | p.V915_K916insVHR | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
RET V915_K916insVHR | unknown |