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Gene ABL1
Variant K596*
Impact List nonsense
Protein Effect loss of function - predicted
Gene Variant Descriptions ABL1 K596* results in a premature truncation of the Abl1 protein at amino acid 596 of 1130 (UniProt.org). Due to the loss of multiple functional domains, including the DNA-binding domain (UniProt.org), K596* is predicted to lead to a loss of Abl1 protein function.
Associated Drug Resistance
Category Variants Paths

ABL1 mutant ABL1 inact mut ABL1 K596*

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Transcript NM_005157.6
gDNA chr9:g.130884076A>T
cDNA c.1786A>T
Protein p.K596*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005157.6 chr9:g.130884076A>T c.1786A>T p.K596* RefSeq GRCh38/hg38
NM_005157 chr9:g.130884076A>T c.1786A>T p.K596* RefSeq GRCh38/hg38
NM_005157.5 chr9:g.130884076A>T c.1786A>T p.K596* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries