ABL1 E1085K
Gene Variant Detail

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Gene ABL1
Variant E1085K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ABL1 E1085K lies within the F-actin-binding region of the Abl1 protein (UniProt.org). E1085K has been identified in sequencing studies (PMID: 27245685), but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Nov 2025).
Associated Drug Resistance
Category Variants Paths

ABL1 mutant ABL1 E1085K

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Transcript NM_005157.6
gDNA chr9:g.130885543G>A
cDNA c.3253G>A
Protein p.E1085K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005157.6 chr9:g.130885543G>A c.3253G>A p.E1085K RefSeq GRCh38/hg38
NM_005157 chr9:g.130885543G>A c.3253G>A p.E1085K RefSeq GRCh38/hg38
NM_005157.5 chr9:g.130885543G>A c.3253G>A p.E1085K RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References