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Gene RET
Variant M1009T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RET M1009T lies within the protein kinase domain of the Ret protein (UniProt.org). M1009T has been identified in sequencing studies (PMID: 27149458, PMID: 24429398, PMID: 35181378), but has not been biochemically characterized and therefore, its effect on Ret protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

RET mutant RET M1009T

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Transcript NM_020975.6
gDNA chr10:g.43124969T>C
cDNA c.3026T>C
Protein p.M1009T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_020975.6 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_001406760.1 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_001406744.1 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_020975 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_020630.5 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_020975.5 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_001406743.1 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_020630 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_001406759.1 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38
NM_020630.7 chr10:g.43124969T>C c.3026T>C p.M1009T RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References