KIT exon17
Gene Variant Detail

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Gene KIT
Variant exon17
Impact List unknown
Protein Effect unknown
Gene Variant Descriptions KIT exon 17 (amino acids 788-828) indicates an unspecified mutation has occurred in exon 17 of the KIT gene.
Associated Drug Resistance
Category Variants Paths

KIT mutant KIT exon17

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05366816 Phase II Regorafenib Sunitinib ctDNA-Guided Sunitinib And Regorafenib Therapy for GIST Recruiting USA 0
NCT04116541 Phase II Alectinib Dabrafenib + Trametinib Cabozantinib Avapritinib A Study Evaluating the Activity of Anti-cancer Treatments Targeting Tumor Molecular Alterations/Characteristics in Advanced / Metastatic Tumors. (MegaMOST) Recruiting FRA 0
NCT05609942 Phase Ib/II Elenestinib Azacitidine + Elenestinib Study of Elenestinib (BLU-263) in Advanced Systemic Mastocytosis (AdvSM) and and Other KIT Altered Hematologic Malignancies (AZURE) Terminated USA | NOR | NLD | FRA | ESP | DEU | BEL 0
NCT06087263 Phase II Regorafenib Phase 2 Study to Evaluate the Efficacy of Regorafenib in Specific GIST Mutation Subsets (KIT Exon 17, 18, or 14 Mutation and SDHB Deficient GIST) in the Post-imatinib Second-line Setting. Recruiting USA 0
NCT02638766 Phase II Regorafenib Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST (REGISTRI) Completed ITA | FRA | ESP 0
NCT07171203 Phase I Dalfampridine + Imatinib Neoadjuvant Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor Not yet recruiting USA 0
NCT05734105 Phase III Ripretinib Sunitinib A Study of Ripretinib Vs Sunitinib in Patients with Advanced GIST with Specific KIT Exon Mutations Who Were Previously Treated with Imatinib (INSIGHT) Recruiting USA | POL | NOR | NLD | ITA | GBR | FRA | ESP | DEU | CAN | BRA | AUS 3