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Therapy Name Elenestinib
Synonyms
Therapy Description

Elenestinib (BLU-263) inhibits KIT D816V, which potentially leads to decreased cell proliferation (Blood (2022) 140 (Supplement 1): 6877–6878; NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Elenestinib BLU-263|BLU 263|BLU263 KIT Inhibitor 57 Elenestinib (BLU-263) inhibits KIT D816V, which potentially leads to decreased cell proliferation (Blood (2022) 140 (Supplement 1): 6877–6878; NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05609942 Phase Ib/II Elenestinib Azacitidine + Elenestinib Study of Elenestinib (BLU-263) in Advanced Systemic Mastocytosis (AdvSM) and and Other KIT Altered Hematologic Malignancies (AZURE) Recruiting USA | NOR | NLD | FRA | ESP | DEU | BEL 0
NCT04910685 Phase II Elenestinib (HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis Recruiting USA | NOR | NLD | ITA | GBR | FRA | ESP | DEU | CHE | BEL | AUT | AUS 1


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