Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene ARID2
Variant H1495fs
Impact List frameshift
Protein Effect loss of function - predicted
Gene Variant Descriptions ARID2 H1495fs results in a change in the amino acid sequence of the Arid2 protein beginning at 1495 of 1835, likely resulting in premature truncation of the functional protein (UniProt.org). Due to the loss of the C2H2-type zinc finger domain (PMID: 32071245), H1495fs is predicted to lead to a loss of Arid2 protein function.
Associated Drug Resistance
Category Variants Paths

ARID2 mutant ARID2 inact mut ARID2 H1495fs

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_152641.4
gDNA chr12:g.(45852605_45852606)
cDNA c.(4483_4482)
Protein p.H1495fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006719272 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38
NM_152641.4 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38
NM_001347839.1 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38
NM_001347839.2 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38
XM_006719272.4 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38
NM_152641.3 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38
XM_047428489.1 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38
NM_152641 chr12:g.(45852605_45852606) c.(4483_4482) p.H1495fs RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References