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Gene ARID2
Variant G1605fs
Impact List frameshift
Protein Effect loss of function - predicted
Gene Variant Descriptions ARID2 G1605fs results in a change in the amino acid sequence of the Arid2 protein beginning at aa 1605 of 1835, likely resulting in premature truncation of the functional protein (UniProt.org). Due to the loss of the C2H2-type zinc finger domain (PMID: 32071245), G1605fs is predicted to lead to a loss of Arid2 protein function.
Associated Drug Resistance
Category Variants Paths

ARID2 mutant ARID2 inact mut ARID2 G1605fs

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Transcript NM_152641.4
gDNA chr12:g.(45860839_45860840)
cDNA c.(4813_4812)
Protein p.G1605fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006719272 chr12:g.(45860839_45860840) c.(4813_4812) p.G1605fs RefSeq GRCh38/hg38
NM_152641.3 chr12:g.(45860839_45860840) c.(4813_4812) p.G1605fs RefSeq GRCh38/hg38
XM_006719272.4 chr12:g.(45860839_45860840) c.(4813_4812) p.G1605fs RefSeq GRCh38/hg38
NM_001347839.1 chr12:g.(45860839_45860840) c.(4813_4812) p.G1605fs RefSeq GRCh38/hg38
NM_152641 chr12:g.(45860839_45860840) c.(4813_4812) p.G1605fs RefSeq GRCh38/hg38
NM_001347839.2 chr12:g.(45860839_45860840) c.(4813_4812) p.G1605fs RefSeq GRCh38/hg38
NM_152641.4 chr12:g.(45860839_45860840) c.(4813_4812) p.G1605fs RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References