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| Gene | ABL1 |
| Variant | P918S |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | ABL1 P918S lies within the DNA-binding domain of the Abl1 protein (UniProt.org). P918S has been identified in the scientific literature (PMID: 27900369), but has not been biochemically characterized and therefore, its effect on Abl1 protein function is unknown (PubMed, Nov 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
ABL1 mutant ABL1 P918S |
| Transcript | NM_005157.6 |
| gDNA | chr9:g.130885042C>T |
| cDNA | c.2752C>T |
| Protein | p.P918S |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_005157.6 | chr9:g.130885042C>T | c.2752C>T | p.P918S | RefSeq | GRCh38/hg38 |
| NM_005157 | chr9:g.130885042C>T | c.2752C>T | p.P918S | RefSeq | GRCh38/hg38 |
| NM_007313 | chr9:g.130884985C>T | c.2752C>T | p.P918S | RefSeq | GRCh38/hg38 |
| NM_007313.3 | chr9:g.130884985C>T | c.2752C>T | p.P918S | RefSeq | GRCh38/hg38 |
| NM_007313.2 | chr9:g.130884985C>T | c.2752C>T | p.P918S | RefSeq | GRCh38/hg38 |
| NM_005157.5 | chr9:g.130885042C>T | c.2752C>T | p.P918S | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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