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Gene ALK
Variant V66G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ALK V66G lies within the extracellular domain of the Alk protein (UniProt.org). V66G has not been characterized in the scientific literature and therefore, its effect on Alk protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ALK mutant ALK V66G

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Transcript NM_004304.5
gDNA chr2:g.29920463A>C
cDNA c.197T>G
Protein p.V66G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004304.5 chr2:g.29920463A>C c.197T>G p.V66G RefSeq GRCh38/hg38
NM_004304.4 chr2:g.29920463A>C c.197T>G p.V66G RefSeq GRCh38/hg38
NM_004304 chr2:g.29920463A>C c.197T>G p.V66G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References